CD274 and neoplasm: The in vivo anti-tumor efficacy of 53L10, 53 P, and atezolizumab (the clinically validated anti-human PD-L1 antibody, which showed in vitro the highest efficacy among the validated mAbs) was compared in A-549 (human alveolar basal epithelial adenocarcinoma cell line) xenograft mouse model (Fig. 7).