As a control for specificity, Li-7 cancer cells expressing lower levels of PD-L1 and 5T4 (Fig. 3) compared with the above-mentioned cell lines, were used in parallel assays and the tribodies showed lower increases of cytotoxic effects than their corresponding combinations, in comparison with the two highly PD-L1-positive cell lines mentioned above, thus confirming the specificity of the treatments. This evidence concerns the gene CD274 and cancer.