PRR15 and non-small cell lung carcinoma: In other primary human NSCLC cells (pNSCLC-2 and pNSCLC-3), and in immortalized A549 cells, stable PRR15 knockdown via shPRR15-1#-expressing lentivirus (refer to Fig. 4) similarly resulted in mitochondrial depolarization (Fig. 5G) and apoptosis (Fig. 5I).