In addition, elevated PRL levels were detected in all stages of OC.[6] As a result, elevated levels of PRL and PRLRs in OC tissues indicate the presence of a potential PRL loop that supports tumor growth in an autocrine manner.[4] Studies have shown that PRL increases the survival rate of OC cells by stimulating proliferation and inhibiting apoptosis.[3,4] Since PRL is involved in processes that support carcinogenesis, it has been suggested as a biomarker for the diagnosis of OC.[4]. The gene discussed is PRL; the disease is neoplasm.