CCT3 and breast carcinoma: In developed regions, the 5-year survival rate exceeds 80%, largely due to early detection, diagnosis, and access to effective treatment.[79] Bioinformatics analysis of CCT subunit expression in breast cancer reveals that CCT2, CCT3, CCT5, CCT6A, CCT7, and CCT8 are significantly upregulated, with their expression levels positively correlated with tumor stage.