On the contrary, obesity was still associated with eGFRcystatin c (OR = 0.990, 95% CI: 0.984–0.997, P < .05), BUN levels (OR = 1.065, 95% CI: 1.036–1.096, P < .05), and cystatin C levels (OR = 1.051, 95% CI: 1.016–1.088, P < .05), the same result was also shown in LASSO (Fig. 8). The gene discussed is CST3; the disease is Obesity.