However, the association between OSA and eGFRcystatin c (OR = 0.981, 95% CI: 0.968–0.994, P < .05) and cystatin C levels (OR = 1.103, 95% CI: 1.026–1.186, P < .05) remained statistically significant even after adjusting for hypertension, as illustrated in Figure 8. The gene discussed is CST3; the disease is hypertensive disorder.