PJA2 and metastatic malignant neoplasm in the lymph nodes: Additionally, the association between the expression of PJA2 and the clinicopathological characteristics of the CRC cohort indicated that PJA2 expression was negatively correlated with pT stage, lymph node metastasis, vascular invasion, and nerve invasion, suggesting that PJA2 may be a crucial target in suppressing CRC progression (Table S1, Supporting Information).