Analysis of mRNA levels revealed that Mtarc1 mRNA was not detectable in Mtarc1 KO mice (Figure 3L), there were no significant differences in inflammatory gene expression between genotypes (Figure 3M), and Col1a1 and Timp1 mRNA expression was significantly decreased in Mtarc1 KO mice (Figure 3N) consistent with decreased liver fibrosis. Here, TIMP1 is linked to Hepatic fibrosis.