TNF and psoriasis: This case report presents an instance of the paradoxical induction of psoriasis by TNF-α inhibitors (TNFis) and discussed the clinical, pathological features and therapeutic considerations for TNFis induced psoriasis (TNFiIP), including the assessment of the necessity of discontinuing TNFi, topical corticosteroid therapy, and exploration of alternative biologics such as IL⁃12/IL⁃23 inhibitors.