In addition, we found that PM20D1 could be a potential biomarker for predicting the prognosis of GC patients, the AUC of PM20D1 in predicting poor prognosis in GC patients was 0.886, with a cutoff value of 3.33 ng/mL, sensitivity of 81.4%, and specificity of 83.9%. This evidence concerns the gene PM20D1 and gastric cancer.