To further determine the expression levels of the three candidate genes in ovarian cancer, we further analyzed the expression levels of the three candidate genes in the GSE209964 dataset and the TCGA database, and the analysis results of GSE209964 data showed that the expression levels of TFAM, HSPE1, and CYC1 in high-grade serous ovarian cancer were significantly higher than healthy fallopian tube. The gene discussed is HSPE1; the disease is ovarian carcinoma.