EPCAM and neoplasm: Building on previous studies that enhanced the capture efficiency of circulating tumor cells (CTCs) using immunolipid magnetic bead (IMB) systems modified with specific antibodies (44, 45), our research has achieved significant technological advancements: Firstly, we employed a reverse evaporation method for IMB preparation and optimized the ratio of EpCAM to Vimentin antibodies, thereby enhancing the uniformity and stability of CTC capture.