In this study, variables such as gender, age, educational level, living situation, daily exercise habits, clinical stage, disease course, treatment method, presence of chronic conditions, BMI, hemoglobin levels, serum albumin, glucose, potassium ion concentration, magnesium ion concentration, PSQI score, and HADS score were incorporated into a multivariate logistic regression analysis to ascertain their influence on CRF in lung cancer patients. This evidence concerns the gene ALB and lung cancer.