According to the results obtained from the ESTIMATE algorithm, CST2 exhibits a significant positive correlation with the ESTIMATEScore, ImmuneScore, and StromalScore across different tumor types such as GBM, UCEC, KIRP, LUSC, KIRC, SARC, COAD, READ, BLCA, LIHC, HNSC, STAD, ESCA, THYM, PAAD, PCPG, THCA, and LGG (Figure 6A). The gene discussed is CST2; the disease is neoplasm.