For example, phenylethanol glycosides from Cistanche tubulosa can prevent rat liver fibrosis induced by bovine serum albumin through the gut microbiota (Qi et al., 2025); Si-Ni-San can effectively alleviate liver injury by regulating gut microbiota dysbiosis and enhancing intestinal barrier function (Li et al., 2025). The gene discussed is ALB; the disease is Hepatic fibrosis.