The results revealed that genes such as PPARG, TNF, PTGS2, TGF-β1, and RELA may be the core targets of QgYp for the treatment of HF, and found that the pathways through which QgYp acted on HF included IL-7 signaling pathway, TNF signaling pathway, NF-κB signaling pathway, and TGF-β signaling pathway. Here, PTGS2 is linked to hydrops fetalis.