Similarly, we verified the diagnostic value of these genes for T2DM as follows: DKK3 (AUC, 0.866), CDKN1A (AUC, 0.801), PLA1A (AUC, 0.774), RDH10 (AUC, 0.767), RGS16 (AUC, 0.739), DACT2 (AUC, 0.722), LIPG (AUC, 0.716) (Figure 5B). The gene discussed is RGS16; the disease is type 2 diabetes mellitus.