Notably, among the DEGs were genes associated with cartilage development, or chondrogenesis, including extracellular matrix genes Col2a1, Col9a1, Col9a2, Acan (Aggrecan), and Comp (Cartilage oligomeric matrix protein), as well as Mia/Cdrap1 (Melanoma inhibitory activity) and Snorc (Small novel rich in cartilage). The gene discussed is COL9A2; the disease is melanoma.