Genetic studies have shown a distinct human leukocyte antigen (HLA) profile for KPD, with a significantly lower prevalence of the type 1 diabetes (T1D)-susceptible haplotype HLA-DRB1*09:01 and a higher prevalence of the protective haplotypes HLA-DRB1*15:01 and/or HLA-DRB1*15:02 [7]. This evidence concerns the gene HLA-DRB1 and type 1 diabetes mellitus.