FiO2: fraction of inspired oxygen; PaO2: partial pressure of oxygen in arterial blood; COPD: chronic obstructive pulmonary disease; NT-proBNP: N-terminal pro-brain natriuretic peptide; ECG: electrocardiogram; MI: myocardial infarction; LV: left ventricular; LVH: left ventricular hypertrophy; RAD: right axis deviation; LBBB: left bundle branch block; AHF: acute heart failure. This evidence concerns the gene NPPB and chronic obstructive pulmonary disease.