FTO and obesity due to melanocortin 4 receptor deficiency: Gholamalizadeh et al. found that carriers of the wild-type A allele of the FTO rs9939609 polymorphism have a significantly higher total body fat percentage [30], a finding that is supported by a meta-analysis by Wang et al., which also showed that the minor A allele was significantly linked to higher chances of obesity and metabolic syndrome in Chinese participants [31].