Now, we know that Kufs disease with progressive myoclonus epilepsy (type A) is associated with mutations in the CLN6 gene, while Kufs disease with dementia and motor disturbances (type B) is linked to mutations in the CTSF gene (also known as CLN13) [10, 48, 49]. The gene discussed is CTSF; the disease is adult neuronal ceroid lipofuscinosis.