SELPLG and colorectal carcinoma: Our previous studies have shown that B. breve CCFM683, B. longum CCFM681, and B. pseudocatenulatum MY40C had different CLA production capabilities in vitro, and had different regulatory effects on intestinal immunity and mechanical barrier.20,23,27 Therefore, a spontaneous CRC model was constructed using C57BL/6J ApcMin+ mice to explore the effect of CLA-producing Bifidobacterium on CRC.