PRKDC and neoplasm: To further reinforce the link between METTL3, DNA‐PKcs, and anlotinib sensitivity as established previously, and to discuss its potential clinical implications, tumour xenograft models were constructed among nude mice through MG63 cells consistently transfected with METTL3 lentivirus or control lentivirus and concurrently with PRKDC shRNA lentivirus or control shRNA lentivirus.