Remarkably, co‐IP revealed that Beclin‐1 was successfully precipitated by the DNA‐PKcs antibody, whereas DNA‐PKcs was pulled down by the anti‐Beclin‐1 antibody in MG63 cells and human osteosarcoma tissues, providing evidence for the interplay between DNA‐PKcs and Beclin‐1 (Figure 3C). Here, BECN1 is linked to osteosarcoma.