Interestingly, central carbon metabolism in cancer (HK2, MAPK3, MYC, PFKP, PKM2, SLC16A3), galactose metabolism (B4GALT2, HK2, PFKP) and fructose and mannose metabolism (HK2, PFKFB4, PFKP) are associated with metabolism. Here, HK2 is linked to cancer.