They modulate various growth factors such as VEGF, FGF, and PDGF, which are essential for these processes.96,97 AXL is expressed in endothelial and vascular smooth muscle cells, where it supports the stabilization and survival of endothelial cells and contributes to tissue remodeling, wound healing, and vessel integrity.98 During neoplasm formation, both AXL and its ligand GAS6 are often overexpressed. The gene discussed is GAS6; the disease is neoplasm.