FLT4 and breast cancer: This emphasizes the significant role of AXL in invasion and migration processes.76 Furthermore, AXL regulates genes associated with metastasis (e.g., somatostatin receptor 2 (SSTR2), fms-related receptor tyrosine kinase 4 (FLT4), matrix metalloproteinase 10 (MMP10), kisspeptin-1 (KISS1), collagen type IV alpha 2 chain (COL4A2), RAR-related orphan receptor B (RORB)) and is linked to the expression of stem cell markers.77 It also facilitates the migration and invasion of breast cancer stem cells.