The intimacy of this PI3K/AKT: DGC interaction has promise in treatment of DMD, with findings in myotubes treated with valproic acid in vitro showing PI3K/AKT pathway activation and less apoptosis and valproic acid‐treated mdx/utrn(−/−) mice showing less muscle fibrosis, inflammatory cells and sarcolemmal damage and increased integrity.208. Here, UTRN is linked to Duchenne muscular dystrophy.