Specifically, TWEAK levels were 3.3 higher in the perilymph than blood of TB mice (19.25 ± 6.56 pg/mL versus 5.80 ± 4.14 pg/mL, P < 0.0001, Two-Way ANOVA), while TNF-α levels were 1.6 times higher in the perilymph than blood (20.59 ± 1.62 pg/mL versus 13.05 ± 2.29 pg/mL, P < 0.016, Two-Way ANOVA) (Fig. 7C). Here, TNF is linked to tuberculosis.