Alterations in the FGFR gene are found in a wide range of cancer entities, with a frequency range of 3–7% in GC/GEJA, and FGFR1 mutation, FGFR2 amplification, and FGFR3 rearrangement are the most common FGFR alterations in GC (Helsten et al. 2016). This evidence concerns the gene FGFR1 and gastric cancer.