Meta-analyses have shown elevated levels of pro- and anti-inflammatory cytokines and chemokines in adult major depression (aMDD), including IL-6, CRP, TNF-α, IL-1ra, IL-1β, IFN-γ, IL-10, IL-18 and a few other [9, 10]. The gene discussed is IFNG; the disease is acromesomelic dysplasia 3.