CENPF and colorectal carcinoma: Furthermore, multivariate Cox regression analysis demonstrated that high CENPF protein expression was an independent predictor for both DFS and OS in CRC patients (HR 5.282, 95% CI 3.162 to 8.822, p < 0.001; HR 2.074, 95% CI 1.192 to 3.607, p = 0.01, respectively) (Table 1).