METTL3 and neoplasm: Additionally, a retrospective study suggested that F. nucleatum could induce m6A methylation to promote metastasis in esophageal squamous carcinoma through a methyltransferase-like 3 (METTL3)/YTH domain family protein 1 (YTHDF1)/myelocytomatosis oncogene (c-Myc) axis, after extracting and analyzing tumor tissues from 22 patients [101].