EB virus (EBV) possesses the propensity to activate multiple oncogenic pathways related to nasopharyngeal carcinoma, including PI3K-AKT, mechanistic target of rapamycin (mTOR), NF-κB, and JAK-STAT, through its encoded proteins latent membrane protein 1 (LMP1), latent membrane protein 2A (LMP2A), Epstein-Barr nuclear antigen 1 (EBNA1), as well as non-coding RNA such as BamHI A rightward transcript microRNA (BART miRNA). Here, MTOR is linked to nasopharyngeal carcinoma.