IFNA1 and systemic lupus erythematosus: Type I interferonopathy is the pathogenic concept of an autoimmune disease group characterized by excessive type I interferon (IFN) secretion caused genetically and non-genetically, including systemic lupus erythematosus (SLE) (8), rheumatic arthritis, systemic sclerosis, Sjögren’s syndrome, and dermatomyositis.