Specifically, GCKR‐mediated branched‐chain amino acids were associated with insulin‐resistant GDM, and multiple acylcarnitines were associated with insulin‐deficient GDM; only two metabolites were oriented in the same direction in the two subtypes, suggesting a mechanism by which the GCKR‐regulated distinct metabolome is involved in the development of different subtypes of GDM [29]. Here, GCKR is linked to gestational diabetes.