FKBP8 and colorectal carcinoma: Numbers of researches have indicated that circRNAs could regulate the stability of their binding proteins.[15, 16] To verify whether circSATB1 could affect the stability of RNF25, LYN, and FKBP8 protein, we detected their mRNA and protein levels in CRC cells with circSATB1 knockdown or overexpression.