Furthermore, while humans with heterozygous NF2 mutations develop schwannomas associated with the inherited disorder neurofibromatosis type 2, Nf2 hemizygous mice do not exhibit the same phenotype[10] (Table S1D, Supplementary Table), making them an inaccurate model for studying human NF2 mutant phenotypes. This evidence concerns the gene NF2 and neurofibromatosis.