LIMA1 and metabolic dysfunction-associated steatotic liver disease: LIM domain and actin‐binding protein 1 (LIMA1), also known as epithelial protein lost in tumors (EPLIN), plays a critical role in regulating the actin cytoskeleton.[15] Recent research has highlighted LIMA1's involvement in key cellular processes such as cell migration, cytoskeletal dynamics, cell cycle regulation, gene regulation, and angiogenesis.[15, 16] While past studies have shown LIMA1's impact on cholesterol uptake and cellular metabolism,[16, 17] its influence on regulating hepatocyte steatosis and MASLD progression requires further investigation.