HMGB1 and infection: High mobility group box 1 (HMGB1), a DNA chaperone in the nucleus that maintains chromosomal structure and function, translocates from the nucleus to the extracellular space under stress conditions, thereby regulating inflammation and immune responses in response to infection and tissue damage.[29] HMGB1 release from the nucleus was observed starting 1 h after light exposure (Figure 5k); this release was confirmed to be time‐dependent through immunoblotting (Figure S7k, Supporting Information).