MUTYH and acute kidney injury: Previous studies have shown that the BER signaling coordinated by the DNA glycosylase MUTYH and OGG1 under tight control can repair damaged DNA.[11b] In this study, our results showed that only deficiency of the BER protein, MUTYH, aggravated cisplatin‐induced DNA damage and AKI, as evidenced by increased 8‐oxoG, γH2AX foci, markers of kidney injury, and cell death, when compared with WT mice.