As a key immunoregulatory factor, ACOD1 has been implicated in various diseases, including cardiovascular diseases,[61, 62, 63] lung diseases,[35, 36, 59, 64] cancer,[65, 66] parasitic infections,[67] and autoimmune disorders.[68, 69] These studies consistently highlight how ACOD1 dysregulation affects inflammation and oxidative stress across different pathological contexts. The gene discussed is ACOD1; the disease is cancer.