ACOD1 and Obesity: Nrf2 has been widely recognized as a downstream target of ACOD1, playing a crucial role in mediating anti‐inflammatory and antioxidant responses.[30, 41, 51, 52, 53, 54] To elucidate the downstream mechanisms of ACOD1 in the context of aggravated lung injury in obesity, we assessed Nrf2 expression levels in both NCD and HFD mice.