Given that JAK inhibition had the greatest effect on post‐influenza MRSA pneumonia, and IL‐6 activates the JAK/STAT pathway, we also investigated how deficiency of IL‐6 signaling might affect host susceptibility to post‐influenza bacterial pneumonia. Here, SOAT1 is linked to Methicillin-Resistant Staphylococcus Aureus Pneumonia.