Transcripts for several candidate genes for obesity were absent in the whole brain or absent in specific regions of the brain (Cyp17a1, Gdf15, Gpr151, Lmx1b, Olig3, Sbk1, Sim1, Skor1, Tnni3k). This evidence concerns the gene TNNI3K and obesity due to melanocortin 4 receptor deficiency.