DGKB and nervous system disorder: This region contains five candidate genes associated with various biological functions: ETS variant 1 (ETV1) related to motor-neuron development [38, 39], diacylglycerol kinase beta (DGKB) involved in skeletal fragility and stature [40–42], alkylglycerol monooxygenase (AGMO) linked to neurological disorder [43], mesenchyme homeobox 2 (MEOX2) associated with development of chick embryo [44, 45], isoprenoid synthase domain containing (ISPD) related to muscle development of [46, 47].