CD86 and colitis: Although we did not observe any alterations to cDC proportion, cDC function, or DC maturation (as measured by expression of CD86) in the populations derived from LDHB expressing proDCs after transfer (Supplementary Fig. 8b–d), suggesting that cDCs are similar in both conditions, these experiments did not directly demonstrate a relationship between LDHB restoration in pDC and colitis.