Gender, race, BMI, education level, PIR, smoking status, diabetes, stroke, lung disease, CHF, CVD, cancer or malignancy, opioids use, NSAIDs use, statins use, WBC, RBC, PLT, BNP and CRP were significantly different in the chronic pain group compared with the non-chronic pain group (P < 0.05, Table 1). The gene discussed is CRP; the disease is Stroke.