BAALC binder of MAP3K1 and KLF4 (BAALC), a regulator of developing neuroectoderm tissues overexpressed in acute leukemia and GBM [58], and a target of SOX2 in differentiated GBM cells [26], was upregulated in HF2303 SDCs (Fig 7C). The gene discussed is MAP3K1; the disease is acute leukemia.