In addition, our patient had other risk factors of ESRD associated with lupus nephritis such as race (nonwhite), eGFR at baseline (36.6 mL/min/1.73 m2), hypocomplementaemia (C3 26 mg/l, C4 4 mg/l, and CH50 < 14 U/mL) and renal histology (class IV) [26, 29]. Here, C3 is linked to lupus nephritis.