Based on these observations, we evaluated the prevalence and localized expression pattern of CCR2 protein in human tumors using mQIF panels containing the markers DAPI, CK, CCR2, CD11b, and CD68 in >1,000 primary human tumors including NSCLC (two cohorts, N = 411), CRC (two cohorts, N = 350), and PDAC (one cohort, N = 228) represented in tissue microarrays (Supplementary Table S14). Here, ITGAM is linked to colorectal carcinoma.