CD86 and neoplasm: In DCs collected from tumor-draining lymph nodes of mTAK-500–treated animals, we observed increased expression of CD80 and CD86 3 days after treatment (1,040.20 ± 188.83 gMFI CD80 and 1,143.20 ± 146.49 gMFI CD86 in 10 μg/kg mTAK-500–treated animals vs. 278.40 ± 24.25 gMFI CD80 and 3.28 ± 97.01 gMFI CD86 in vehicle-treated animals; Fig. 4B).