E. gingivalis is present in various forms of periodontitis, including peri-implantitis (6), as an intrusive pathogen in light of its red blood cell phagocytosis capability, and of the degradation of host cellular immunity correlating with upregulated TNFα and IL8 as reported by Bao et al. (15). Here, CXCL8 is linked to Peri-Implantitis.