Using real-time PCR, the association between the SARS-CoV-2 receptor angiotensin-converting enzyme 2 (ACE2) and miRNA-200c-3p and miRNA-421-5p as well as interleukin-6 (IL-6) was examined in the saliva of moderate (G1, n = 10) and severe (G2, n = 10) periodontitis subjects. Here, ACE2 is linked to periodontitis.