We found that PDL-1 on CD14− CD16+ monocyte [OR (95% CI): 0.98 (0.97–1.00)], CD64 on CD14+ CD16− monocyte [OR (95% CI): 0.99 (0.98–1.00)] were protective against HF. The gene discussed is FCGR1A; the disease is hydrops fetalis.