We found that CD127 on CD45RA+ CD4+ [OR (95% CI): 1.03 (1.00–1.05)], CD25hi CD45RA- CD4 not Treg AC (CD25hi CD45RA- CD4 not Treg Activated) [OR (95% CI): 1.01 (1.00–1.02)], CD39 on CD39+ activated Treg [OR (95%CI): 1.02 (1.00–1.04)], CD28 on secreting Treg [OR (95% CI): 1.02 (1.00–1.03)], CD39+ CD8br%CD8br [OR (95% CI): 1.02 (1.00–1.03)], CD127- CD8br AC (CD127- CD8br Activated Cytotoxic T lymphocytes) [OR (95% CI): 1.03 (1.00–1.06)] were risk factors for HF. The gene discussed is CD28; the disease is hydrops fetalis.