NOTCH1 and diffuse large B-cell lymphoma: Similar subtypes exist in DLBCL, which is divided into five genetic subtypes including: (1) EZB having genetic alterations in the BCL2 and EZH2 locus, (2) BN2 having genetic alterations in BCL6 and NOTCH1, (3) MDC, (4) N1 having mutations in NOTCH1, and (5) primary mediastinal B-cell lymphomas [33].